Dera Ghazi Khan (Urdu and Punjabi: ضلع ڈيره غازى خان, Saraiki: ضلع دیرہ غازی خان, Balochi: ڈیرہ غازی خان) is a district in the Punjab province of Pakistan. Its capital is the town of Dera Ghazi Khan.
The Sulaiman Mountains rise to a height of 10,000 feet (3,000 m) in the north of the district.
The city was founded at the close of the 15th century and named after Nawab Ghazi Khan Mirani, son of Nawab Haji Khan Mirani, a Balochi chieftain, who had declared independence from the Langah Dynasty‘s Sultans of Multan. Together with two other Deras i.e. settlements, Dera Ismail Khan and Dera Fateh Khan, it gave its name to Derajat. Derajat eventually came into the possession of the British after the Sikh War in 1849 and was divided into two districts: Dera Ghazi Khan and Dera Ismail Khan. After the independence, many of the city’s Hindu residents settled in Derawal Nagar colony of Delhi, India. The district of Rajanpur was later carved out of the Dera Ghazi Khan district.
Based on the surveys of 2004–2005, Dera Ghazi Khan district is considered one of the twenty poorest districts of Pakistan with about 51% of its population living under the poverty line.